Just when the healthcare industry and its frontline caregivers were recovering from more than two years of managing enormous COVID-19 patient loads, the “triple threat” of COVID-19, influenza and RSV arrived with a vengeance in early fall. Children under five, and especially those less than six months old, were affected the most. Fall and winter surges of respiratory illnesses are not uncommon, especially for this age group, but cases were critically high this year since mask-wearing and social distancing during the pandemic reduced natural immunity levels. It seems as if the healthcare community is treating three years’ worth of pediatric respiratory illnesses in a single season.